ACTION OF ACTINOMYCIN DON ANIMAL CELLS AND VIRUSE

Basis of actinomycin action. I. DNA binding and inhibition of RNA-polymerase synthetic reactions by actinomycin.

Basis of actinomycin action. II. Effect of actinomycin on the nucleoside triphosphate-inorganic pyrophosphate exchange.

In a preceding paper,1 we have described the effect of actinomycin on the different synthetic reactions catalyzed by RNAt-polymerase, and the relationship between actinomycin action and the structure and base composition of DNA. This paper presents the results of experiments concerned with the effect of actinomycin on the nucleoside triphosphate-inorganic pyrophosphate exchange reaction. Materi...

Action of actinomycin and puromycin upon frog oocyte maturation.

In amphibians, as well as in other vertebrates, occytes start to mature under the action of hypophyseal gonadotropic hormones. (In this paper the term 'maturation' implies the transformation into ripe eggs of oocytes that have finished growing.) In the course of maturation the oocytes themselves and the follicle cells surrounding them undergo changes; the changes of these two cell types are not...

Prevention of Hormone Action by Local Application of Actinomycin D.

Fipronil: mechanisms of action on various organisms and future relevance for animal models studies

Because insects had developed resistance to several insecticides, today, neonicotinoids and fiproles are used to combat pests. The difference between this two classes of insecticides is that fipronil acts by inhibiting the receptors of nervous cells, while neonicotinoids perturbs the neuronal transmission. The suitable properties of fipronil make that its use to be more obvious on the pesticide...